Hyperbaric Oxygen was born in 1662, when a British doctor, Nathaniel Henshaw, created an airtight chamber where oxygen bellows and valves were used to compress and decompress.

In the 1930s, a Brazilian doctor named Álvaro Osório de Almeida recognized the benefits of HBOT (Hyperbaric Oxygen Therapy) and published several papers on the effects of high doses of oxygen on animal and human tumors.  In 1937, Albert Behnke and Louis Shaw published research by the US Navy to treat decompression sickness using HBOT.